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Multi-Scale Functional and Molecular Imaging

We work at the interface of engineering, physics, biology and medicine to devise new in vivo imaging tools that can tackle challenges unapproachable with existing modalities

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Selected Recent Papers

Holographic transcranial ultrasound neuromodulation enhances stimulation efficacy by cooperatively recruiting distributed brain circuits. Nature Biomedical Engineering, 2026

Optoacoustic-guided magnetic microrobot platform for precision drug delivery. Advanced Materials, 2026

Synergistic integration of materials in medical microrobotics for imaging and actuation. Nature Reviews Materials, 2025

Upconversion nanoparticle-covalent organic framework core-shell particles as therapeutic microrobots trackable with optoacoustic imaging. Advanced Materials, 2025

Imaging the brain by traversing the skull with light and sound. Nature Biomedical Engineering, 2025

Unlocking NIR-II photoluminescence in 2D copper tetrasilicate nanosheets through flame spray synthesis. Advanced Materials, 2025

WISDEM: a hybrid wireless integrated sensing detector for simultaneous EEG and MRI. Nature Methods, 2025

Concurrent optoacoustic tomography and magnetic resonance imaging of resting-state functional connectivity in the mouse brain. Nature Communications, 2024

Hierarchical nanostructures as acoustically manipulatable multifunctional agents in dynamic fluid flow. Advanced Materials, 2024

Multimodal optoacoustic imaging: methods and contrast materials. Chemical Society Reviews, 2024

Cortex-wide transcranial localization microscopy with fluorescently labeled red blood cells. Nature Communications, 2024

Tonic and burst-like locus coeruleus stimulation causally shifts network activity across the cortical hierarchy. Nature Neuroscience, 2024

Deep optoacoustic localization microangiography of ischemic stroke in mice. Nature Communications, 2023

A sound solution for deep-brain imaging. Nature Methods, 2023

Spiral volumetric optoacoustic tomography for imaging whole-body biodynamics in small animals. Nature Protocols, 2023

Main News

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Paul Wrede selected as the 2026 Global Schmidt Science Fellow ________________________________

SNSF funds development of a new microscopy method for stroke research » ________________________________

Using ultrasound holograms to influence brain networks » ________________________________

HELIOS: Breakthrough in optoacoustic imaging » ________________________________

New grant on in vivo imaging of norepinephrine release » ________________________________

Quanyu Zhou is honoured by ETH Medal for her doctoral thesis » ________________________________

Delivering medicines with microscopic flowers » ________________________________

Daniel Razansky is awarded the IPPA James Smith Prize » ________________________________

Big congrats to Eva Remlova for winning the ETH Medal » ________________________________

We are part of the new EU Horizon consortium SWEEPICS » ________________________________

BE-LIGHT: where light meets learning » ________________________________

Towards a cure for chronic wounds » ________________________________

Optoacoustic-guided focused ultrasound for neurosurgery » ________________________________

New molecular imaging toolset for studying Alzheimer’s disease » ________________________________

SRF interview on the future of microrobotics » ________________________________

Development of world’s first hybrid MRI-MSOT scanner under SNSF funding » ________________________________

Interview with Daniel Razansky » ________________________________

Learn about the history